BDBM50401167 CHEMBL2205792

SMILES CN1CCC(C)(C)c2cc3c(-c4ccc(s4)C(=O)N4CCCCC4)c4ccc(cc4sc3cc12)=[N+](C)C

InChI Key InChIKey=JSKAIXJQBYQAQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401167   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human His10-tagged P-gp ATPase activity expressed in BHK cells assessed as verapamil-induced inorganic phosphate release incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed