BDBM50416072 CHEMBL1084632
SMILES CCCS(=O)(=O)Nc1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F
InChI Key InChIKey=OOBVFAPEUYZCPP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50416072
Affinity DataIC50: 15.8nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition of dexamethasone-induce...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair