BDBM50417023 CHEMBL1258901

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@]2(O)\C=C\CC(F)(F)C(F)(F)C(F)(F)F

InChI Key InChIKey=QXQSOKYJCXQSQX-FAAAOKLOSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50417023   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.13E+3nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.81E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  35.5nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  129nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed