BDBM50417267 CHEMBL1271768

SMILES CN1[C@@H](COC1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=ONNLHBQOUYFFMZ-VIFPVBQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417267   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50417267(CHEMBL1271768)
Affinity DataIC50:  16nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50417267(CHEMBL1271768)
Affinity DataIC50:  15.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells by ethidium accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed