BDBM50426499 CHEMBL2323581

SMILES COC(OC)[C@@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1

InChI Key InChIKey=VXPAMWVVWOOAQG-FRFSOERESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426499   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50426499(CHEMBL2323581)
Affinity DataKi:  0.540nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50426499(CHEMBL2323581)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human 5-HT2B receptor transfected in CHO cell assessed as decrease in 5-HT-induced IP1 production preincubated for 5 mins befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed