BDBM50428137 CHEMBL2336043

SMILES CCCC(CCC)C(=O)N[C@H](COc1ccc(\C=C\C(=O)NO)cc1OC)Cc1c[nH]c2ccccc12

InChI Key InChIKey=XXQDYFIYFPZTLZ-JLQMKUNGSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50428137   

TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  940nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  377nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  322nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  180nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50428137(CHEMBL2336043)
Affinity DataIC50:  390nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed