BDBM50428696 CHEMBL2333120

SMILES CC(C)Nc1c(nnc2cc(ccc12)N1CCOCC1)C(N)=O

InChI Key InChIKey=YMNHISNDWVXKND-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50428696   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428696(CHEMBL2333120)
Affinity DataIC50:  9nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428696(CHEMBL2333120)
Affinity DataIC50:  22nMAssay Description:Inhibition of CSF1R (unknown origin) by TR-FRET assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428696(CHEMBL2333120)
Affinity DataIC50:  262nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by TR-FRET assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed