BDBM50429201 CHEMBL2338554

SMILES CC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccccc2)N2[C@H](O)CC[C@H](NC(=O)\C(NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](COS([O-])(=O)=O)OC)C(C)C)[C@@H](C)OC1=O)=C\C)C2=O

InChI Key InChIKey=MWNJAHQOLGNHPR-NPMPHBRVSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429201   

TargetNeutrophil elastase(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50429201(CHEMBL2338554)
Affinity DataIC50:  78nMAssay Description:Inhibition of human neutrophil elastase-induced antiproliferative activity expressed in BEAS2B cells assessed as cytoprotectivity after 24 hrs by MTT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50429201(CHEMBL2338554)
Affinity DataIC50:  93nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50429201(CHEMBL2338554)
Affinity DataIC50:  144nMAssay Description:Inhibition of human neutrophil elastase assessed as proteolysis using N-(methoxysuccinyl)-Ala-Ala-Pro-Val-p-nitroanilide substrate incubated for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed