BDBM50430175 CHEMBL584646::GNF-Pf-1115

SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)C#N

InChI Key InChIKey=CDHUKLSCXZSGMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430175   

TargetP2X purinoceptor 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50430175(CHEMBL584646 | GNF-Pf-1115)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 4(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50430175(CHEMBL584646 | GNF-Pf-1115)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed