BDBM50430889 CHEMBL2336952
SMILES Cn1c2ccccc2c(O)c(C(N=Nc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c2nnn[nH]2)c1=O
InChI Key InChIKey=IPTMMSQYEIIGOR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50430889
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...More data for this Ligand-Target Pair