BDBM50430895 CHEMBL2336509

SMILES Cc1ccc(cc1NC(=O)CSc1nnc(Cc2ccccc2)n1C)[N+]([O-])=O

InChI Key InChIKey=KQPNNSYSJTXPFR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430895   

TargetProstaglandin E synthase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50430895(CHEMBL2336509)
Affinity DataIC50:  800nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed