BDBM50430899 CHEMBL2336505

SMILES CCn1c(CNC(=O)c2ccc(C)cc2)nnc1SCC(=O)Nc1cc(ccc1C)[N+]([O-])=O

InChI Key InChIKey=SGEGUTQDQLVQKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430899   

TargetProstaglandin E synthase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50430899(CHEMBL2336505)
Affinity DataIC50:  54nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed