BDBM50430934 CHEMBL2336944
SMILES OC(=O)COc1ccc(Br)cc1C=c1c(=C)[nH]n(-c2ccc(Cl)c(Cl)c2)c1=O
InChI Key InChIKey=OSPAEDWIQLTHSC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50430934
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair