BDBM50430937 CHEMBL2336521
SMILES Clc1ccc(\C=C\c2cc(nc3ccc4ccccc4c23)-c2ccc(cc2)-c2ccccc2)cc1
InChI Key InChIKey=CIOXBDFHBJODCS-JLHYYAGUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50430937
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair