BDBM50430939 CHEMBL2336519
SMILES Cc1cc(C)c2oc(nc2c1)-c1ccc(C)c(NC(=O)c2cccc(c2)[N+]([O-])=O)c1
InChI Key InChIKey=OIYNIULYIODNSU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50430939
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair