BDBM50430942 CHEMBL2336516
SMILES Cc1ccc(cc1NC(=O)CSc1nnc(CNc2c(C)cccc2C)n1C)[N+]([O-])=O
InChI Key InChIKey=WAPDTPUXKPBRHS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50430942
Affinity DataIC50: 9.30nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...More data for this Ligand-Target Pair