BDBM50435344 CHEMBL2391541

SMILES COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1

InChI Key InChIKey=HGRHWEAUHXYNNP-UHFFFAOYSA-N

Data  55 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50435344   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  936nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  936nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  4.25E+3nMAssay Description:Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi:  4.27E+3nMAssay Description:Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from alpha4beta2 nACh receptor in HEK293 cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Ucl School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from human recombinant 5-HT3 receptor expressed in HEK293T cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed