BDBM50435518 CHEMBL2392486

SMILES COC(=O)N[C@@H]1CC[C@H](C1)n1nnc2cnc3[nH]ccc3c12

InChI Key InChIKey=MAOJWRIAIOAPKQ-RKDXNWHRSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435518   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435518(CHEMBL2392486)
Affinity DataKi:  12nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435518(CHEMBL2392486)
Affinity DataKi:  33nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435518(CHEMBL2392486)
Affinity DataEC50:  395nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed