BDBM50435524 CHEMBL2392485

SMILES CC(C)(C)OC(=O)N[C@@H]1CC[C@H](C1)n1nnc2cnc3[nH]ccc3c12

InChI Key InChIKey=TVVCYONNWZJIJD-GHMZBOCLSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435524   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435524(CHEMBL2392485)
Affinity DataKi:  2.40nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435524(CHEMBL2392485)
Affinity DataKi:  10nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435524(CHEMBL2392485)
Affinity DataEC50:  127nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed