BDBM50436237 CHEMBL603141

SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)N1CCCC(C1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=MOQCFMZWVKQBAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436237   

TargetRho-related GTP-binding protein RhoC(Homo sapiens)
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50436237(CHEMBL603141)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming protein RhoA(Homo sapiens (Human))
College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50436237(CHEMBL603141)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of RhoC-mediated pathway in human PC3 cells assessed as inhibition of SRE-regulated gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed