BDBM50437663 CHEMBL2408059

SMILES CCN(CC)c1ncc(N(CC)C(=O)c2ccsc2)c(N[C@@H](Cc2ccc(OC(=O)N3CCCC3)cc2)C(O)=O)n1

InChI Key InChIKey=KGDZUGSBEBVXKQ-QHCPKHFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50437663   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in presence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  36nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed