BDBM50438673 CHEMBL2414535

SMILES CS(=O)(=O)c1ccc(cc1)-c1cccn2nc(Nc3ccc(cc3)C(=O)N3CCOCC3)nc12

InChI Key InChIKey=JWGTVLHHDDDEOE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438673   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438673(CHEMBL2414535)
Affinity DataKi:  0.400nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50438673(CHEMBL2414535)
Affinity DataIC50:  53nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as reduction of phosphorylated STAT5 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed