BDBM50438998 CHEMBL2420679
SMILES COc1ccc2ccc(-c3cncc(F)c3)c(Cl)c2c1
InChI Key InChIKey=RPIYHUIWRDPDMU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50438998
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of CYP19 in human placental microsomes using [1beta-3H]androstenedione as substrate by 3H2O-methodMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 454nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using 1,2[3H]-progesterone as substrate in presence of NADPHMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair