BDBM50439211 CHEMBL2418817

SMILES Cc1sc(Nc2ccc(Cl)cc2F)nc1C(=O)N1CCc2ncccc2C1

InChI Key InChIKey=MSTRPYBYQABRCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439211   

TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439211(CHEMBL2418817)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439211(CHEMBL2418817)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed