BDBM50439250 CHEMBL2419044
SMILES CC(C)C[C@@H](NC(=O)[C@@H]1CNC[C@@H](C1)N1CC(=O)N(CC1(C)C)c1ccccc1C)c1ccc(F)cn1
InChI Key InChIKey=SURFEDDEQIGIAF-QQKQFIJSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50439250
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human plasma renin by competitive radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsin-activated human recombinant renin using (Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg) as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of cynomolgus monkey plasma renin assessed as angiotensin 1 level after 60 mins by competitive radioimmunoassayMore data for this Ligand-Target Pair