BDBM50439296 CHEMBL2419524::US10696692, Example 287
SMILES O=C(NCc1ccc(cc1)S(=O)(=O)C1CCN(CC1)C1COC1)N1Cc2ccncc2C1
InChI Key InChIKey=PFMSCDXGGGWGEB-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50439296
Affinity DataIC50: 31nMAssay Description:Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using (S)- warfarin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 17.2nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair