BDBM50441287 CHEMBL2431506
SMILES CCOC(=O)c1c(O)csc1Nc1ccc(Cl)c(c1)C(F)(F)F
InChI Key InChIKey=SAHMXCNZNRCQTH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50441287
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
State Key Laboratory Of Bioreactor Engineering
Curated by ChEMBL
State Key Laboratory Of Bioreactor Engineering
Curated by ChEMBL
Affinity DataIC50: 751nMAssay Description:Inhibition of Plasmodium falciparum DHODH (Phe158 to Ser569) expressed in Escherichia coli BL21 using dihydroorotate as substrate measured every 30 s...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
State Key Laboratory Of Bioreactor Engineering
Curated by ChEMBL
State Key Laboratory Of Bioreactor Engineering
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged human DHODH (Met30 to Arg396) expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate measur...More data for this Ligand-Target Pair