BDBM50442169 CHEMBL2441343

SMILES Cc1ccn(CC(=O)N2CCc3cc(ccc23)-c2cn(C)c3ncnc(N)c23)n1

InChI Key InChIKey=HJXSOEITHNLYIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442169   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442169(CHEMBL2441343)
Affinity DataIC50:  58nMAssay Description:Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed