BDBM50446847 CHEMBL3115074

SMILES C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccccc1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=ADSVKUMNMQPBKC-LAUBAEHRSA-N

Data  8 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50446847   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi:  54nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing the human EP1 (Genbank accession number AY275470) or EP4 (Genban...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi:  1.55E+3nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing the human EP1 (Genbank accession number AY275470) or EP4 (Genban...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi: >1.27E+4nMAssay Description:Displacement of [3H]-PGE2 from human EP3 receptor by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi: >1.40E+4nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing the human EP1 (Genbank accession number AY275470) or EP4 (Genban...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi: >1.75E+4nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing the human EP1 (Genbank accession number AY275470) or EP4 (Genban...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM50446847(CHEMBL3115074)
Affinity DataKi: >1.75E+4nMAssay Description:Displacement of [3H]-PGE2 from human EP1 receptor by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed