BDBM50447178 CHEMBL1596118::US10752581, Compound 1

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nccs2)c1O

InChI Key InChIKey=CENSVXZQMJBVHY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50447178   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human epithelial 15-LOX2 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50:  5.10E+3nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human reticulocyte 15-LOX1 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed