BDBM50447196 CHEMBL3113202::US10752581, Compound 72

SMILES Oc1c(Cl)cccc1CNc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1

InChI Key InChIKey=NJYXWXLBXPBUFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447196   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447196(CHEMBL3113202 | US10752581, Compound 72)
Affinity DataIC50:  2.30E+3nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447196(CHEMBL3113202 | US10752581, Compound 72)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed