BDBM50450500 CHEMBL4164465
SMILES OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl
InChI Key InChIKey=VEKPUFJACSQBMV-ZWKOTPCHSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50450500
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPM2 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPM4 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPM8 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPC4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPC5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPC6 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPC3 (unknown origin)More data for this Ligand-Target Pair