BDBM50452083 CHEMBL4206169

SMILES Cc1cc2c3[nH]c(Nc4c(Cl)cncc4Cl)nc3cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2o1

InChI Key InChIKey=RHXLFYLMFDIDOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452083   

TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50452083(CHEMBL4206169)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed