BDBM50458125 CHEMBL4217352

SMILES OP(O)(=O)Cc1ccc(NC(=O)C2CCN(CC2)C(=O)OCc2cc(Cl)cc(Cl)c2)cc1

InChI Key InChIKey=CYOVYGWNDHLPBF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50458125   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50458125(CHEMBL4217352)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human ENPP2 using FS3 as substrate measured every 5 mins for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50458125(CHEMBL4217352)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ENPP2 in human A2058 cells using LPC as substrate preincubated for 15 mins followed by substrate addition measured after 3 hrs by LC-MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50458125(CHEMBL4217352)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human ENPP2 using bis-pNPP as substrate measured every 10 secs for 10 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50458125(CHEMBL4217352)
Affinity DataIC50:  136nMAssay Description:Inhibition of ENPP2 in human plasma using LPC as substrate preincubated for 15 mins followed by substrate addition measured after 3 hrs by LC-MS/MS a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50458125(CHEMBL4217352)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of ENPP2 in human SKHEP1 cells using LPC as substrate preincubated for 15 mins followed by substrate addition measured after 3 hrs by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed