BDBM50459010 CHEMBL4213919

SMILES CNC(=O)c1nnc2ccc(cc2c1N[C@@H](C)c1nn(C)cc1C)-c1ccc(OCCCN(C)C)nc1

InChI Key InChIKey=IIPXDBRFRKJQIH-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459010   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50459010(CHEMBL4213919)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 residue in human HT-29 cells measured after 1 hr by Hoechst staining based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50459010(CHEMBL4213919)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATR in human HT-29 cells measured after 1 hr by Hoechst 33258 staining based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed