BDBM50460459 CHEMBL4228006
SMILES COC(=O)Nc1ccc(cc1)-c1cnnc(c1)[C@H](Cc1ccccc1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1
InChI Key InChIKey=VQGKRPKUGUYGOV-BULTVDLSSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50460459
Affinity DataKi: 7nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate measured after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 268nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: 840nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: >6.22E+3nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: >1.47E+4nMAssay Description:Inhibition of human TPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >2.97E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.81E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair