BDBM50460700 CHEMBL4227812
SMILES COc1ccc(Nc2nccc(NC(=O)Nc3cccc(NC(=O)C=C)c3)n2)c(OC)c1
InChI Key InChIKey=IZXAWICOIQJFFX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50460700
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 391nMAssay Description:Inhibition of EGFR L858R/T790M mutant phosphorylation in human NCI-H1975 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M mutant cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology Co. Itd.
Curated by ChEMBL
Affinity DataIC50: 348nMAssay Description:Inhibition of recombinant human GST-tagged wild-type EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair