BDBM50461390 CHEMBL4225256

SMILES CNC(=O)c1ccc(Sc2cccc(NC(=S)Nc3cccc(c3)C(F)(F)F)c2)nc1

InChI Key InChIKey=NGXHRENOZZFICP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50461390   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50461390(CHEMBL4225256)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 as substrate measured after 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50461390(CHEMBL4225256)
Affinity DataIC50:  973nMAssay Description:Inhibition of B-Raf (unknown origin) using MEK1 as substrate measured after 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50461390(CHEMBL4225256)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labelled peptide as substrate pretreated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed