BDBM50462099 CHEMBL4246684

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CN)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key InChIKey=CKSDDOVOKAXVKT-KFTUOKHQSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462099   

TargetMannan-binding lectin serine protease 2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462099(CHEMBL4246684)
Affinity DataKi:  180nMAssay Description:Inhibition of MASP-2 (unknown origin) using Z-L-LysSBzl hydrochloride as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetMannan-binding lectin serine protease 2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462099(CHEMBL4246684)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of MASP-2-mediated C4 deposition in human serum after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetMannan-binding lectin serine protease 1(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462099(CHEMBL4246684)
Affinity DataIC50:  220nMAssay Description:Inhibition of MASP-1-mediated C3 deposition in human serum after 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed