BDBM50462129 CHEMBL4244166

SMILES [#6]-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(cc1)C#C[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6@H](-[#7](-[#6]-1)-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6])C([#6])([#6])[#6])-[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#6]-c2ccccc-12)-[#6](=O)-[#7]-1-[#6][Si;v4]([#6])([#6])[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#6]-c2ccccc-12

InChI Key InChIKey=SOUZAGJRYQSXAP-UZNJVIDBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462129   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462129(CHEMBL4244166)
Affinity DataIC50:  4nMAssay Description:Inhibition of N-terminal His-tagged XIAP BIR2-3 domain (125 to 356 residues) C202A/C213G mutant (unknown origin) using fluorescein labeled SMAC pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462129(CHEMBL4244166)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal His-tagged XIAP BIR3 domain (241 to 356 residues) (unknown origin) using fluorescein labeled SMAC peptide as substrate after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed