BDBM50463710 CHEMBL4245241

SMILES Nc1onc2nc(cc(-c3ccc(NC(=O)Nc4ccc(F)cc4)cc3)c12)-c1ccccc1

InChI Key InChIKey=DMEJUOSQIGUPQF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463710   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463710(CHEMBL4245241)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of human PDGFRbeta using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463710(CHEMBL4245241)
Affinity DataIC50:  696nMAssay Description:Inhibition of human KDR using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463710(CHEMBL4245241)
Affinity DataIC50:  449nMAssay Description:Inhibition of human FLT3 using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed