BDBM50463846 CHEMBL4243837

SMILES Fc1cccnc1[C@@H](NC(=O)c1ccc(=O)[nH]c1)c1ccc(OC(F)(F)F)c(F)c1

InChI Key InChIKey=KZJHWEJVIDNHJM-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463846   

LigandPNGBDBM50463846(CHEMBL4243837)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50463846(CHEMBL4243837)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50463846(CHEMBL4243837)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed