BDBM50465359 CHEMBL4279052::US10669276, Example 11
SMILES CNc1nc(Nc2ccc(c(F)c2)-n2cc(C)nc2C)nc2N(CC(C)(C)c12)c1ccc(F)cc1
InChI Key InChIKey=IKJZUNNQQQRVRP-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50465359
Affinity DataEC50: 33nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair