BDBM50466301 CHEMBL4284025

SMILES [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(OC(OCCNC1CCN(CC1)c1ccc(C(=O)NS(=O)(=O)c3ccc(NCC5CCOCC5)c(c3)[N+]([O-])=O)c(Oc3cnc5[nH]ccc5c3)c1)[C@@H]2C)O4

InChI Key InChIKey=IROMHTYFTLXWQY-XVQFLZNBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466301   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466301(CHEMBL4284025)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466301(CHEMBL4284025)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed