BDBM50467143 CHEMBL4283970

SMILES OC(=O)CCCC(=O)Nc1cc(ncn1)N1CCOCC1

InChI Key InChIKey=FDPQKRUPPHXZMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467143   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467143(CHEMBL4283970)
Affinity DataIC50:  53nMAssay Description:Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467143(CHEMBL4283970)
Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467143(CHEMBL4283970)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed