BDBM50467146 CHEMBL1379917

SMILES Fc1ccc(cc1)C(=O)Nc1cc(ncn1)N1CCOCC1

InChI Key InChIKey=TXVGFVZTROUDRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467146   

TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467146(CHEMBL1379917)
Affinity DataIC50:  96nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467146(CHEMBL1379917)
Affinity DataIC50:  63nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50467146(CHEMBL1379917)
Affinity DataIC50:  131nMAssay Description:Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed