BDBM50467166 CHEMBL4278031
SMILES COc1cccc(Nc2cc(Nc3cccc(Cl)c3)ncn2)c1
InChI Key InChIKey=XOHURCPHBLRKTQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50467166
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 974nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair