BDBM50470543 CHEMBL4286154

SMILES CC(C)[C@H](NC(=O)[C@@H]1OC(=O)[C@H]1C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1

InChI Key InChIKey=NEQHFOKLQNEKPO-LWYYNNOASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50470543   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
New Mexico Institute Of Mining And Technology

Curated by ChEMBL
LigandPNGBDBM50470543(CHEMBL4286154)
Affinity DataIC50:  45nMAssay Description:Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetmRNA cap guanine-N7 methyltransferase(Homo sapiens)
New Mexico Institute Of Mining And Technology

Curated by ChEMBL
LigandPNGBDBM50470543(CHEMBL4286154)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetmRNA cap guanine-N7 methyltransferase(Homo sapiens)
New Mexico Institute Of Mining And Technology

Curated by ChEMBL
LigandPNGBDBM50470543(CHEMBL4286154)
Affinity DataIC50:  4.18E+3nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed