BDBM50471982 CHEMBL147384

SMILES Cc1oc(nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)-c1ccc(F)cc1

InChI Key InChIKey=QTRNCEZOJHHDGS-HKBQPEDESA-N

Data  2 KI  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50471982   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataKi:  1.60nMAssay Description:Inhibition by 50% of in vitro binding to Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataKi:  56nMAssay Description:Tested in vitro for inhibiting the 50% binding of Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataEC50:  1.5nMAssay Description:Ability to promote differentiation of C3H10T1/2 stem cells to adipocytes using lipogenesis assay mediated through activation of Peroxisome proliferat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataEC50:  0.126nMAssay Description:Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataEC50:  257nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataEC50:  0.126nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50471982(CHEMBL147384)
Affinity DataEC50:  257nMAssay Description:In vitro transactivation of Peroxisome proliferator activated receptor alpha.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed