BDBM50474796 CHEMBL64941

SMILES Oc1ccc2[nH]c(CN3CCC(Cc4ccc(F)cc4)CC3)nc2c1

InChI Key InChIKey=PAFKHYPPLMSWPU-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50474796   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50474796(CHEMBL64941)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to NR1/NR2B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50474796(CHEMBL64941)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human NR1a/NR2B receptor expressed in mouse fibroblast LMTK cells assessed as inhibition of Glu/Gly induced Ca2+ influxMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50474796(CHEMBL64941)
Affinity DataIC50:  47nMAssay Description:Antagonist activity against NR1a/NR2B receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influxMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed